SAMe is a supplement formed in the body by an enzymatic reaction between adenosine-triphosphate (ATP) and methionine. It was discovered in 1952 in Italy and has been researched and manufactured there. SAMe works closely with folic acid and vitamin B-12, and functions as a methyl donor. This nutrient carries and donates methyl molecules necessary to facilitate the manufacture of DNA and brain neurotransmitters.* Tissue levels of SAMe are typically low in the elderly.

Suggested Use:  As a dietary supplement, take 1 tablet, 1 to 2 times daily, preferably on an empty stomach. Refrigeration recommended after opening.

S u p p l e m e n t   F a c t s    Amount   Per Serving     % Daily   Value   Vitamin B-6 (as Pyridoxine HCl)     2 MG         100%        Folic Acid     200 MCG         50%        Vitamin B-12 (as Cyanocobalamin)     50 MCG         833%        S-Adenosyl L-Methionine Disulphate Tosylate     400 MCG         †            (providing 200 mg S-Adenosyl L-Methionine "SAMe")     -------             †          * Percent Daily Values are based on 2,000 calorie diet.       † Daily Value not established.

 
Other Ingredients:  Di-Calcium Phosphate, Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Croscamellose Sodium, Polymethacrylate, Titanium Dioxide, Food Glaze, Riboflavin.

Free Of:  Sugar, salt, yeast, corn, soy, wheat, milk, preservatives or additives.

Warning:  Individuals with bipolar (manic) depression should not take SAMe unless under professional medical supervision.